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Titulo Artículo : Incorporating Informatics for Integrating Biology and the Bedside (i2b2) into Predoctoral Trainee Curriculum to Evaluate Student‐Generated Hypotheses
Titulo Revista: Clinical and Translational Science

ISBN

1752-8062
Autores Douglas G. Peters
Chesney K. Richter
Welley S.
James A. Pawelczyk
Kathleen M. Schieffer
Año de publicacion 2015

Suplemento

Numero 6 Volumen 8
Pagina Inicial 729 Pagina Final 733
Idioma: Inglés Base de datos bibliográfica: Biblioteca Virtual en Salud(BVS)
Resumen : As part of the Clinical and Translational Science Institute predoctoral TL1 training program at the Pennsylvania State University, a multidisciplinary team of predoctoral trainees representing the Chemistry, Neurosurgery, Nutritional Sciences, and Public Health Sciences departments were introduced to the NIH‐sponsored Informatics for Integrating Biology and the Bedside (i2b2) database to test the following student‐generated hypothesis: children with iron deficiency anemia (IDA) are at increased risk of attention deficit‐hyperactivity disorder (ADHD). Children aged 4–12 and 4–17 years were categorized into IDA and control groups. De‐identified medical records from the Penn State Milton S. Hershey Medical Center (HMC) and the Virginia Commonwealth University Medical Center (VCUMC) were used for the analysis. Overall, ADHD prevalence at each institution was lower than 2011 state estimates. There was a significant association between IDA and ADHD in the 4–17‐year‐old age group for all children (OR: 1.902 [95% CI: 1.363–2.656]), Caucasian children (OR: 1.802 [95% CI: 1.133–2.864]), and African American children (OR: 1.865 [95% CI: 1.152–3.021]). Clinical and Translational Science Award (CTSA) infrastructure is particularly useful for trainees to answer de novo scientific questions with minimal additional training and technical expertise. Moreover, projects can be expanded by collaborating within the CTSA network.
Palabras Claves : Anemia
Cobalamin
Attention‐deficit/hyperactivity
Bioinformatics

Tipo de acceso:

libre Disponibilidad Link Externo
Publico Objetivo: Pregrado , Posgrado , Medicos , Investigadores , Otros profesionales de la salud ,